Role of Contrast-Enhanced Computed Tomography (CECT) in Hepatocellular Carcinoma (HCC) in Adults with Chronic Liver disease (CLD)

Authors

  • Jahanzaib Superior University, Lahore
  • Imad Ud Din Khan Superior University, Lahore
  • Wishma Noor Superior University, Lahore
  • Adeena Noor Superior University, Lahore
  • Nosheen Naimat Superior University, Lahore
  • Minahil Mohsin Superior University, Lahore
  • Rahiba Sarfaraz Superior University, Lahore

DOI:

https://doi.org/10.37762/jgnahs.125

Keywords:

Chronic Liver Disease, Hepatocellular Carcinoma, Magnetic Resonance Imagin

Abstract

OBJECTIVES

To evaluate the diagnostic accuracy of CECT in identifying HCC in adults with chronic liver disease and compare it with other imaging modalities such as MRI and ultrasonography.

METHODOLOGY

This study involved 200 adult patients diagnosed with CLD. CECT was performed on all patients suspected of HCC. Imaging findings were correlated with histopathological results obtained after biopsy. Sensitivity, specificity, and diagnostic accuracy were calculated. Statistical analysis was performed using SPSS v25.0.

RESULTS

CECT had a sensitivity of 89%, specificity of 94%, and an overall diagnostic accuracy of 92%. The findings were compared with MRI and ultrasonography, where CECT demonstrated superior diagnostic performance in lesion characterization, arterial phase enhancement, and detection of small tumors (<2 cm).

CONCLUSION

CECT plays an integral role in the diagnosis and management of HCC in patients with CLD. Its high diagnostic accuracy, particularly in detecting early-stage tumors, makes it a preferred imaging modality.

Author Biographies

Jahanzaib, Superior University, Lahore

Demonstrator & Program
Leader Faculty of Allied Health
Sciences, Superior University, Lahore

Imad Ud Din Khan, Superior University, Lahore

Demonstrator & Program Leader
OTT, Faculty of Allied Health
Sciences, Superior University, Lahore

Wishma Noor, Superior University, Lahore

Student of Faculty of Allied Health
Sciences, Superior University, Lahore

Adeena Noor, Superior University, Lahore

Student of Faculty of Allied Health
Sciences, Superior University, Lahore

Nosheen Naimat, Superior University, Lahore

Student of Faculty of Allied Health
Sciences, Superior University, Lahore

Minahil Mohsin, Superior University, Lahore

Student of Faculty of Allied Health
Sciences, Superior University, Lahore

Rahiba Sarfaraz, Superior University, Lahore

Student of Faculty of Allied Health
Sciences, Superior University, Lahore

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Published

2024-09-30

How to Cite

Jahanzaib, Imad Ud Din Khan, Wishma Noor, Adeena Noor, Nosheen Naimat, Minahil Mohsin, & Rahiba Sarfaraz. (2024). Role of Contrast-Enhanced Computed Tomography (CECT) in Hepatocellular Carcinoma (HCC) in Adults with Chronic Liver disease (CLD). Journal of Gandhara Nursing and Allied Health Sciences, 4(2), 17–19. https://doi.org/10.37762/jgnahs.125