Role of Contrast-Enhanced Computed Tomography (CECT) in Hepatocellular Carcinoma (HCC) in Adults with Chronic Liver disease (CLD)
Keywords:
Chronic Liver Disease, Hepatocellular Carcinoma, Magnetic Resonance ImaginAbstract
OBJECTIVES
To evaluate the diagnostic accuracy of CECT in identifying HCC in adults with chronic liver disease and compare it with other imaging modalities such as MRI and ultrasonography.
METHODOLOGY
This study involved 200 adult patients diagnosed with CLD. CECT was performed on all patients suspected of HCC. Imaging findings were correlated with histopathological results obtained after biopsy. Sensitivity, specificity, and diagnostic accuracy were calculated. Statistical analysis was performed using SPSS v25.0.
RESULTS
CECT had a sensitivity of 89%, specificity of 94%, and an overall diagnostic accuracy of 92%. The findings were compared with MRI and ultrasonography, where CECT demonstrated superior diagnostic performance in lesion characterization, arterial phase enhancement, and detection of small tumors (<2 cm).
CONCLUSION
CECT plays an integral role in the diagnosis and management of HCC in patients with CLD. Its high diagnostic accuracy, particularly in detecting early-stage tumors, makes it a preferred imaging modality.
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Copyright (c) 2024 Jahanzaib, Imad Ud Din Khan, Wishma Noor, Adeena Noor, Nosheen Naimat, Minahil Mohsin, Rahiba Sarfaraz
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